Shareholder Information
The information on this page was last updated on 15 October 2025. The number of shares in issue was 437,018,680.
Significant Shareholdings
| Shareholder | Number | Ordinary Shares % |
|---|---|---|
| CVI Investments, Inc. | 43,151,533 | 9.9% |
| Icahn School of Medicine at Mount Sinai | 37,346,476 | 8.5% |
| Pentwater Capital | 34,049,049 | 7.8% |
| Ruffer LLP | 32,800,000 | 7.5% |
| Jefferson River Capital LLC | 30,755,501 | 7.0% |
| Unicorn Asset Management Limited | 25,797,882 | 5.9% |
| Harwood Capital LLP | 17,061,345 | 3.9% |
| ABRDN World Healthcare Fund | 14,546,533 | 3.3% |
| Vaal Investment Partners | 13,827,903 | 3.2% |
Director Shareholdings
| Director | Number | Ordinary Shares % |
|---|---|---|
| Christopher Mills* | 17,061,345 | 3.9% |
| James McCullough** | 3,242,096 | 0.7% |
| Julian Baines | 1,953,963 | 0.4% |
| Robert Naylor | 693,318 | 0.2% |
| Fergus Fleming | 653,023 | 0.1% |
| Catherine Coste | 385,129 | 0.1% |
* Christopher Mills is partner and Chief Executive Officer of Harwood Capital LLP. Harwood Capital LLP is Investment Manager to North Atlantic Smaller Companies Investment Trust plc and investment adviser to Oryx International Growth Fund Limited. Christopher’s shareholding disclosure is held by North Atlantic Smaller Companies Investment Trust PLC, Oryx International Growth Fund Limited and Harwood Capital LLP.
** James McCullough shareholding includes shares held through his family trust, The McCullough 2020 Irrevocable Trust (the “Trust”).
Shares not in public hands
As at 15 October 2025, the percentage of AIM securities not in public hands was 5.51%. The securities not in public hands include all significant shareholders over 10%, the directors and executive officers who are classed as persons discharging managerial responsibilities. There are no shares held in treasury.
Rights of shareholders
The rights of shareholders are governed by UK law.
Restrictions in transfer of ordinary shares
There are no restrictions on the transfer of the company’s ordinary shares.
UK City Code on Takeover and Mergers
The Company is subject to the provisions of the City Code on Takeover and Mergers.
Other exchanges and trading platforms
All of the Company’s shares are traded on AIM, a market of London Stock Exchange plc, and American Depositary Shares representing the Company’s ordinary shares are listed on the OTCQB. The Company’s shares are not traded on any other exchange or trading platform.