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Shareholder Information

The information on this page was last updated on 5 October 2026. The number of shares in issue was 670,459,333.

Significant Shareholdings

ShareholderNumberOrdinary Shares %
CVI Investments, Inc.86,100,00012.84%
Pentwater Capital68,500,00010.22%
ABRDN World Healthcare Fund66,719,3959.95%
Icahn School of Medicine at Mount Sinai43,501,9896.49%
Ruffer LLP41,150,0006.14%
Unicorn Asset Management Limited38,297,8825.71%
Jefferson River Capital LLC30,755,5014.59%
VenHedge Capital Partners LP27,699,8084.13%

Director Shareholdings

DirectorNumberOrdinary Shares %
Christopher Mills*18,201,6892.71%
James McCullough**3,577,9700.53%
Julian Baines1,953,9630.29%
Catherine Coste1,616,2310.24%
Robert Naylor693,3180.10%
Fergus Fleming674,7700.10%
Erik Lium615,5510.09%

* Christopher Mills is partner and Chief Executive Officer of Harwood Capital LLP. Harwood Capital LLP is Investment Manager to North Atlantic Smaller Companies Investment Trust plc and investment adviser to Oryx International Growth Fund Limited. Christopher’s shareholding disclosure is held by North Atlantic Smaller Companies Investment Trust PLC, Oryx International Growth Fund Limited and Harwood Capital LLP.

** James McCullough shareholding includes shares held through his family trust, The McCullough 2020 Irrevocable Trust (the “Trust”).

Shares not in public hands

As at 5 October 2026, the percentage of AIM securities not in public hands was 27.3%. The securities not in public hands include all significant shareholders over 10%, the directors and executive officers who are classed as persons discharging managerial responsibilities. There are no shares held in treasury.

Outstanding Options and Warrants

As at 5 October 2026, the Company has 43,051,043 share options outstanding, comprising both vested and unvested options. The Company has no warrants outstanding.

Rights of shareholders

The rights of shareholders are governed by UK law.

Restrictions in transfer of ordinary shares

There are no restrictions on the transfer of the company’s ordinary shares.

UK City Code on Takeover and Mergers

The Company is subject to the provisions of the City Code on Takeover and Mergers.

Other exchanges and trading platforms

All of the Company’s shares are traded on AIM, a market of London Stock Exchange plc, and American Depositary Shares representing the Company’s ordinary shares are listed on the OTCQB. The Company’s shares are not traded on any other exchange or trading platform.